Delirium Tremens Background In 1902, Leon Huyghe started working in the local brewery at the ‘Appelhoek’ site, in Melle, Belgium (near Ghent). Documentary evidence dates brewing at the ‘Appelhoek’ site back to 1654. Married to Delfina Van Doorselaer, a brewer’s daughter, Leon had always been fascinated with brewing.  And just four years later (1906), he…